Microsoft Office 2016.
Ive found that Office 2016, especially Outlook 2016, will lock up and want to shutdown, something about some problem that needs fixing.
After much swearing, googling and trying stuff I finally found a fix that seems to work.
1. Go into Outlook > File > Options > Advanced
2. Look for 'Display'
3. SELECT/CHECK the “Disable Hardware graphics acceleration” option.
So far Ive had no problems and it seems to be working great.